@article {987,
	title = {Activation of the Sarcophaga lectin gene promoter in transgenic Drosophila},
	volume = {50},
	year = {Submitted},
	note = {08-10-200906-02-2012NormalDepartment of Cell Biochemistry, Graduate School of Pharmaceutical Sciences, University of Tokyo, Bunkyo-ku, Tokyo, Japan.enghttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve\&db=pubmed\&dopt=Abstract\&list_uids=12111973},
	pages = {131 - 138},
	publisher = {Copyright 2002 Wiley-Liss, Inc.},
	abstract = {We established transgenic Drosophila strains in which the lacZ gene was expressed under the control of the 5{\textquoteright}-upstream regulatory region of the Sarcophaga lectin gene promoter (3.1 kbp). The reporter gene was expressed in the fat bodies of the transgenic larvae when they were immunized by body pricking or treatment with Escherichia coli, which was the same as the Sarcophaga lectin gene expression in Sarcophaga larvae. However, the same reporter gene was found to be expressed constitutively in the digestive tracts of the transgenic larvae even without immunization.},
	keywords = {*Depsipeptides, *Insect Proteins, *Lectins, C-Type, *Peptides, *Promoter Regions, Genetic, *Transcriptional Activation, Animals, Animals, Genetically Modified, Anti-Bacterial Agents/immunology, beta-Galactosidase/genetics, Cell Line, Diptera/genetics/*metabolism, Drosophila melanogaster/genetics/immunology, Escherichia coli/immunology, Genes, Reporter, Lectins/*genetics, Staphylococcus aureus/immunology, Tissue Distribution, Transgenes},
	author = {Tanji, T. and Kobayashi, A. and Natori, S.}
}
@article {546,
	title = {Involvement of insect-derived growth factor (IDGF) in the cell growth of an embryonic cell line of flesh fly},
	volume = {350},
	year = {Submitted},
	note = {08-10-200906-02-2012NormalGraduate School of Pharmaceutical Sciences, The University of Tokyo, Bunkyo-ku, Tokyo 113-0033, Japan.enghttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve\&db=pubmed\&dopt=Abstract\&list_uids=17011515},
	pages = {334 - 338},
	abstract = {Insect-derived growth factor (IDGF) is the first adenosine deaminase-related growth factor (ADGF) purified from the conditioned medium of NIH-Sape-4, an embryonic cell line of Sarcophaga peregrina (flesh fly). Here we show the requirement of IDGF for the growth of NIH-Sape-4 cells. Growth factor activity was abolished by adsorption of IDGF from the conditioned medium of NIH-Sape-4 cells. In addition, knockdown of IDGF gene expression by RNA interference (RNAi) significantly reduced IDGF secretion from the cells following cell growth inhibition. The IDGF gene was strongly expressed in the hemocytes, and IDGF increased the viability of the larval hemocytes. These data provide evidence that IDGF is required for the growth of NIH-Sape-4 cells and possibly for hemocyte viability.},
	keywords = {Animals, Cell Line, Cell Proliferation/drug effects, Cell Survival/drug effects, development/metabolism, Diptera/cytology/growth \&amp, Embryo, Nonmammalian/cytology, Gene Expression, Growth Substances/genetics/pharmacology/*physiology, Hemocytes/cytology/drug effects, Insect Proteins/genetics/pharmacology/*physiology, Larva/cytology/drug effects, RNA Interference},
	author = {Tanaka, Y. and Yamaguchi, S. and Fujii-Taira, I. and Iijima, R. and Natori, S. and Homma, K. J.}
}
