@article {539,
	title = {Expression of sarcotoxin IA gene via a root-specific tob promoter enhanced host resistance against parasitic weeds in tomato plants},
	volume = {25},
	year = {Submitted},
	note = {08-10-200906-02-2012NormalAgricultural Research Organization (ARO), Department of Weed Research, Newe Yaar Research Center, Ramat Yishai, 30095 Ramat, Israel. radi@volcani.agri.gov.ilenghttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve\&db=pubmed\&dopt=Abstract\&list_uids=16217684},
	pages = {297 - 303},
	abstract = {We have developed a simple genetic engineering strategy for conferring resistance against parasitic weeds on host plants. Transgenic tomato plants expressing the sarcotoxin IA gene were grown either in polyethylene bags (PE) or in pots inoculated with Orobanche aegyptiaca seeds. The results indicate that transgenic plants exhibited strong inhibition of parasite growth and significantly increased yield as compared with non-transgenic ones. In both PE and pot systems most of the parasite tubercles attached to the transgenic root plants turned necrotic and developed abnormally. Integration and expression of the gene were confirmed by Southern blot, RT-PCR and Western blot analysis. Our results indicate that the insect gene produced in the plant cells was selectively toxic to the parasite and non-toxic to the host plant.},
	keywords = {development/*physiology, Gene Expression, Germination, Host-Parasite Interactions, Insect Proteins/*genetics/*metabolism, Lycopersicon esculentum/*genetics/*parasitology, Orobanche/growth \&amp, Plant Roots/*metabolism, Plants, Genetically Modified, Promoter Regions, Genetic/*genetics, Seeds},
	author = {Radi, A. and Dina, P. and Guy, A.}
}
@article {546,
	title = {Involvement of insect-derived growth factor (IDGF) in the cell growth of an embryonic cell line of flesh fly},
	volume = {350},
	year = {Submitted},
	note = {08-10-200906-02-2012NormalGraduate School of Pharmaceutical Sciences, The University of Tokyo, Bunkyo-ku, Tokyo 113-0033, Japan.enghttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve\&db=pubmed\&dopt=Abstract\&list_uids=17011515},
	pages = {334 - 338},
	abstract = {Insect-derived growth factor (IDGF) is the first adenosine deaminase-related growth factor (ADGF) purified from the conditioned medium of NIH-Sape-4, an embryonic cell line of Sarcophaga peregrina (flesh fly). Here we show the requirement of IDGF for the growth of NIH-Sape-4 cells. Growth factor activity was abolished by adsorption of IDGF from the conditioned medium of NIH-Sape-4 cells. In addition, knockdown of IDGF gene expression by RNA interference (RNAi) significantly reduced IDGF secretion from the cells following cell growth inhibition. The IDGF gene was strongly expressed in the hemocytes, and IDGF increased the viability of the larval hemocytes. These data provide evidence that IDGF is required for the growth of NIH-Sape-4 cells and possibly for hemocyte viability.},
	keywords = {Animals, Cell Line, Cell Proliferation/drug effects, Cell Survival/drug effects, development/metabolism, Diptera/cytology/growth \&amp, Embryo, Nonmammalian/cytology, Gene Expression, Growth Substances/genetics/pharmacology/*physiology, Hemocytes/cytology/drug effects, Insect Proteins/genetics/pharmacology/*physiology, Larva/cytology/drug effects, RNA Interference},
	author = {Tanaka, Y. and Yamaguchi, S. and Fujii-Taira, I. and Iijima, R. and Natori, S. and Homma, K. J.}
}
